In an effort to help educate our customers, we think it’s important to promote a clear understanding of what peptides are.
How else can you effectively perform research and develop new or improved solutions leveraging peptides? Having a good understanding of what peptides are will help eliminate unnecessary guesswork.
On the most basic level, peptides are substances or compounds created from two or more amino acids. These essential acids are linked in a chain. Complex covalent chemical bonds are formed based on the reaction that the different amino acids have when joined together.
Structurally Similar to Proteins
Keep in mind that peptides are completely organic substances. Their structural makeup of molecules are remarkably similar to proteins and some peptides even operate similarly to proteins. Much like the various different proteins are dictated by the molecules that make them up, peptides are dictated by the number of amino-acid molecules present. In theory, a large variety of combinations haven’t been successfully researched or formulated just yet, leaving plenty of room for future discovery!
Peptide classes range from hormones to antibiotics and to metabolism-influencing compounds.
Leveraging peptides to influence hormones isn’t exactly a new idea. There are published studies from the 1980’s and 1990’s regarding testosterone formation in relation to certain peptides. Back in May of 1990, a group of doctors and researchers found that peptides can be leveraged to stimulate testosterone production in rat cells. Over the past decade, there has been a large plethora of studies regarding similar affects in humans.
Growing beyond the idea that we could leverage peptides to increase testosterone, in 1996 another group discovered the effects that peptides have on human growth hormone. Growth hormone research has been a hot topic since the mid 90’s because of the potential for disease eradication.
Baby steps though… baby steps. A logical step before trying to leverage peptides to eradicate disease? Antibiotics. Antimicrobial peptides have become commonplace. The medical community has worked with big pharma to successfully create a large variety of safe and effective antibiotics with organic peptides at the core of efficacy. First met with some skepticism because of the presumption that antimicrobial peptides would result in hormone irregularities, they’re not considered a healthy alternative to conventional antibiotics. While conventional antibiotics are still more popular, the antimicrobial peptides gain more market share annually.
The most recent peptide research efforts seem to revolve around the effects that peptides can have in metabolic disorders. Here’s a list of some things thought to be treatable through peptide dosing:
-Influencing carbohydrate metabolic rates can help combat obesity and various diseases that form as a result. (Think diabetes)
-Thyroid disorders are thought to be something metabolic peptides can help combat. An alternative to the medications traditionally prescribed, metabolic peptides are thought to have no adverse side effects.
-Liver disease and kidney disease can potentially be prevented or effectively treated through metabolic peptide prescriptions.
The future of peptide manufacturing likely revolves around metabolic peptide research and all the different things we may be able to do with it. More research needs to be completed. Head here to get your own research peptides!
Owji, H, et al. “A Comprehensive Review of Signal Peptides: Structure, Roles, and Applications.” Current Neurology and Neuroscience Reports., U.S. National Library of Medicine, Aug. 2018, www.ncbi.nlm.nih.gov/pubmed/29958716.
Erickson, L D, et al. “Synthetic Alpha-Subunit Peptides Stimulate Testosterone Production in Vitro by Rat Leydig Cells.” Current Neurology and Neuroscience Reports., U.S. National Library of Medicine, May 1990, www.ncbi.nlm.nih.gov/pubmed/1691699.
Argente, J, et al. “Growth Hormone-Releasing Peptides: Clinical and Basic Aspects.” Current Neurology and Neuroscience Reports., U.S. National Library of Medicine, www.ncbi.nlm.nih.gov/pubmed/8950613.