Product Spotlight

What is Anastrozole?

Anastrozole, which may also be referred to as Arimidex, is a non-steroidal aromatase inhibitor. It has a molecular formula of C17H19N5 and a molecular weight of 293.37.  We offer it on gurupeptides.com for laboratory research only.  As we state in our disclaimer, bodily introduction of any kind into humans and/or animals is strictly forbidden by law.  

As an aromatase inhibitor, Anastrozole has been explored as a potential treatment for breast cancer in postmenopausal women.  Anastrozole is particularly effective because it can significantly reduce estrogen levels in women. Estrogen suppression can lead to significantly reduced breast tumor growth rates, both in women and in men suffering from Gynecomastia.

Aromatase and Inhibiting Aromatase

Aromatase is an enzyme that most essential for estrogen production in the body.  Primarily responsible for converting androgen precursors like testosterone, aromatase can naturally synthesize estrogen.  The end result is lower testosterone and higher estrogen.

Aromatase inhibitors work by blocking the conversion.  The different types of inhibitors may have different methods of action.  Some will stop the conversion by reducing testosterone production. Without testosterone being present, it isn’t possible to be converted.  Some inhibitor solutions might render the aromatase enzyme paralyzed, preventing any estrogen synthesis whatsoever. Still others, like Anastrozole, drastically slow the conversion rate by restricting, limiting, and regulating the anastrozole enzymes.

Aromatase Inhibitor Side Effects

Occasionally if you are looking at the side effects list of the product that you’re going to be using, the list doesn’t include side effects included in the whole class of medication the product belongs to.  In an effort to provide full disclosure, we’ve decided to post a list of the main side effects realized by nearly all aromatase inhibitors… Anastrozole included.

  • Loss of bone density – Extended supplementation can lead to higher osteoporosis chances.
  • Joint and muscle pain – Arthralgia and myalgia development has been recognized in various case studies.
  • Vaginal Dryness – Not something the men need to worry about, but women can expect to notice a decrease in the body’s ability to self clean.

Anastrozole Specific Side Effects

Continuing the trend of full disclosure, we’ve included a list of the side effects most frequently recognized in subjects using Anastrozole.  Results vary. Not all subjects notice an adverse effect while others have the misfortune of noticing multiple effects. Age, health, race, and frequency of use may be determining factors of side effect emergency and frequency.

  • Digestive fluctuations – Diarrhea, constipation, nausea, and loss of appetite have all been reported.  These are by far the most common side effects recognized.
  • Mental/Cognitive fluctuations – Not as common as the digestive effects, depression, mood swings, irritability, and apathy are all reported mental/cognitive alterations recognized and reported.
  • Hot Flashes
  • Dry Mouth
  • Mild rash
  • Energy reduction

The Future of Anastrozole

Because of Anastrozole’s efficacy when it comes to breast cancer treatment, many notable people in the medical community believe it could be the key to curing or preventing breast cancer entirely.  Most likely, it will be a combination drug that utilizes Anastrozole, if anything does the trick. More research will be completed in the coming years, as technology improves… We live in a glorious time.

1 Bundred, N J. “Aromatase Inhibitors and Bone Health.” Current Neurology and Neuroscience Reports., U.S. National Library of Medicine, Feb. 2009, www.ncbi.nlm.nih.gov/pubmed/19125005.

2 Nyrop, K A, et al. “Aromatase Inhibitor Associated Arthralgia: the Importance of Oncology Provider-Patient Communication about Side Effects and Potential Management through Physical Activity.” Current Neurology and Neuroscience Reports., U.S. National Library of Medicine, June 2016, www.ncbi.nlm.nih.gov/pubmed/26757739.


3 Wiseman, L R, and J C Adkins. “Anastrozole. A Review of Its Use in the Management of Postmenopausal Women with Advanced Breast Cancer.” Current Neurology and Neuroscience Reports., U.S. National Library of Medicine, Oct. 1998, www.ncbi.nlm.nih.gov/pubmed/9805213.

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