Product Spotlight

What Is Letrozole?

Letrozole is an FDA approved drug for the treatment of breast cancer in postmenopausal women. It is specifically used in cancers that have been shown to be hormone receptor positive or where the exact status is unknown and there is a chance the cancer could be hormonally responsive. It is believed that estrogen can “feed” certain types of breast cancer, stimulating an increased growth of cancer. By reducing the amount of estrogen available in the body tissue with Letrozole, it is believed that breast cancer growth will be halted.Letrozole is a non-steroidal aromatase inhibitor, meaning it’s not a steroid but shares some of the same physiological effects of steroid type medications. For example, Letrozole interrupts the synthesis of estrogen in the body just like a steroid-based medication would. The molecular formula of Letrozole is C17H11N5 and it has a molecular weight of 285.31 g/mol.
As with most prescription drugs, Letrozole is also used for many off label purposes including the treatment of endometriosis and ovarian stimulation in women, gynecomastia (breast growth) in men and to promote spermatogenesis (increasing sperm production) in men. Letrozole can also be used in conjunction with misoprostol for chemical termination of pregnancy. In theory, Letrozole could be used to halt or control the production of estrogen in any males or females taking the drug.

What is Letrozole Prescribed For?

The various uses for Letrozole continue to increase as more clinical studies and laboratory research is done using this particular drug. The FDA-approved use of Letrozole is for postmenopausal, hormonally receptive types of breast cancer in patients who have already had some type of surgery for the cancer as a method of reducing cancer growth.

Letrozole is also commonly used for off-label purposes in both men and women, and those purposes include:

Women are sometimes prescribed Letrozole for the treatment of endometriosis, ovarian stimulation for fertility issues, and in combination with misoprostol for early termination of pregnancy.
Men may be prescribed Letrozole for promoting spermatogenesis, treating gynecomastia, and delaying fusion of growth plates in adolescent boys.
Additional potential uses could theoretically be in combating the effects of excess estrogen production due to anabolic steroid use.

Formulation of Letrozole

Letrozole tablets, sold under the brand name Femara, are taken orally and are imprinted with distinct markings of the letters CG on one side of the pill and FV on the other. They can be identified by their oval shape (biconvex) with flattened tips and beveled edges. They are a film-coated tablet that are dark yellow in color. Letrozole, before being turned into pill form, is an odorless yellowish powder that is almost insoluble in water.

How and Where to Buy Letrozole

Letrozole as a liquid can be purchased under its generic name versus the name brand Femara. It is sold primarily as a research chemical in this form. It is a clear and nearly odorless liquid packaged in glass bottles for shipment. Guru Peptides offers Letrozole 2.5mg per ml x 30ml for research purposes

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