What is Andarine S4?
Andarine, commonly referred to as AS4, And-S4, or just S4, is an investigational selective androgen receptor modulator (SARM) that has gained significant attention in the fitness community for its potent effects on muscle growth, fat loss, and bone density. Unlike anabolic steroids, SARMs like Andarine are highly selective in their action, making them a subject of interest for both bodybuilders and researchers alike. This selectivity allows SARMs to target specific tissues, reducing the risk of widespread side effects.
Andarine S4 has become popular in the fitness world due to its impressive ability to enhance muscle mass and burn fat. However, these physical enhancements represent just a fraction of its potential uses. We offer high-quality Andarine S4 suspended in Polyethylene glycol, intended solely for laboratory and research purposes, at an affordable price.
Beyond Bodybuilding: Andarine S4 in Research
The applications of Andarine S4 extend far beyond bodybuilding. Over the past decade, research has uncovered its potential in treating various medical conditions, particularly those related to bone health and musculoskeletal disorders.
- June 2005: Researchers Jiyun Chen, Juhyun Kim, and James Dalton discovered that Andarine S4 had therapeutic effects on cells from individuals suffering from osteoporosis. This condition, characterized by reduced bone mass and increased fragility, is currently incurable. The study marked the beginning of research into the medical applications of Andarine S4.
- October 2007: Building on their earlier work, James Dalton and his team conducted a study that demonstrated Andarine’s ability to prevent bone loss in ovariectomized rats, a model often used to simulate postmenopausal osteoporosis in humans. The results suggested that Andarine could potentially be used to prevent bone loss in humans as well.
- July 2010: Following Dalton’s research, further studies explored Andarine S4 as a treatment for musculoskeletal diseases. These studies aimed to develop therapeutic regimens for conditions like severe osteoporosis, which affects millions of people worldwide.
- June 2015: A decade after the initial research, scientists began to investigate SARMs like Andarine S4 as potential treatments for a broader range of musculoskeletal disorders. The hope is that SARMs could not only prevent bone loss but also treat conditions such as carpal tunnel syndrome and tendinitis, which are common and often debilitating.
The Future of Andarine S4
The future of Andarine S4 largely depends on the continuation and expansion of research. It is expected that the FDA may approve further human testing for the use of SARMs in treating osteoporosis. There is also potential for Andarine S4 to be used in treating other musculoskeletal disorders. Given the prevalence of conditions like carpal tunnel syndrome and tendinitis, which affect a significant portion of the population, there is a strong possibility that Andarine S4 could play a role in developing new treatments or even cures.
Risks and Side Effects of Andarine S4
Despite its potential, the risks and side effects associated with Andarine S4 cannot be overlooked. Similar to anabolic steroids, common side effects include high blood pressure, hair loss, suppression of natural testosterone production, increased estrogen levels, and acne. These side effects occur whether the SARM is used for bodybuilding or medical treatment. Addressing these adverse effects remains a crucial focus of ongoing research. If researchers can mitigate these risks, Andarine S4 could become a valuable tool in both medical and fitness contexts.
References:
- Chen, Jiyun, et al. “Discovery and Therapeutic Promise of Selective Androgen Receptor Modulators.” Mol Interv., U.S. National Library of Medicine, Nov. 2009, NCBI.
- Kearbey, Jeffrey D., et al. “Selective Androgen Receptor Modulator (SARM) Treatment Prevents Bone Loss and Reduces Body Fat in Ovariectomized Rats.” Pharm Res., U.S. National Library of Medicine, Oct. 2007, NCBI.
- Bhasin, Shalender, and Ravi Jasuja. “Selective Androgen Receptor Modulators (SARMs) as Function Promoting Therapies.” Curr Opin Clin Nutr Metab Care., U.S. National Library of Medicine, Jul. 2010, NCBI.
- Girgis, Christian M., et al. “Therapies for Musculoskeletal Disease: Can we Treat Two Birds with One Stone?” Curr Osteoporos Rep., U.S. National Library of Medicine, Jun. 2015, NCBI.
